Barbiturates

Barbiturates are a class of around 12 compounds derived from barbituric acid. They are central nervous system depressants that can be used as sedatives, hypnotics, anaesthetics or anti-epileptic drugs. Barbiturates can be divided into three main groups according to their duration of action. The ultrashort-acting barbiturates are used clinically as anaesthetics whilst the long-acting barbiturates have anti-convulsing properties. Short-acting compounds can be used as hypnotics and favoured by drug abusers due to their ability to reduce tension and produce a feeling of tranquillity. An overdose of barbiturates can lead to a dramatic fall in blood pressure and body temperature, depressed respiration or coma.

Whole Blood
Post Mortem Blood
Urine
Oral Fluid
Hair
Meconium
Vitreous Humor
Tissue

Cross Reactivity

Analyte Compound
Cross Reactivity %
CR%
Barbiturates
LOD: 17.3 ng/mL
Phenobarbital 100
Secobarbital
184.7
Cyclopentobarbital
132.8

All data in the above table refers to our whole blood matrix.

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