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Fentanyl

Fentanyl is a synthetic opioid, a specific µ-agonist, with approximately 100 times the potency of morphine. The effects of fentanyl are indistinguishable from those produced by insufflation of street heroin, however, fentanyl is much more potent and has high abuse potential.  In the late 1970s, fentanyl appeared in the illicit drug market with over 12 different analogues having been produced clandestinely and identified by the USA DEA. Intravenous administration is most commonly used but fentanyl can also be smoked or insufflated. Fentanyl is extensively metabolised, with only 0.4 to 6% of the dose excreted in urine as unchanged drug.  The main metabolite of fentanyl is norfentanyl.

Product Number: FE3505

Cross Reactivity

AnalyteLODMatricesCompoundsCross Reactivity %
Fentanyl0.67 ng/mlWhole Blood, Post Mortem Blood, UrineFentanyl790
Butrylfentanyl334
para-fluorofentanyl242
Furanylfentanyl154
Benzylfentanyl134
meta-hydroxy-acrylfentanyl125
Thienylfentanyl121
Norfentanyl100
Ocfentanyl69
Acetylfentanyl37
w-hydroxyfentanyl37
(±)cis-3-methylfentanyl31
Ohmefentanyl23
α-methylfentanyl20
3-Methylthiofentanyl19
Norfuranylfentanyl13
Norocfentanyl2
*LOD is standardised to this compound

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